Monthly Archives: June 2011

Recently, 3 publications have assessed in vivo immune modulation in infants in the context of the primary prevention of eczema. In a subgroup analysis of Kukkonen et al., Marschan and colleagues reported increased CRP, IgA, IgE, and IL-10 in infants … Continue reading →

Extending these observations, the hygiene hypothesis suggests, in part, that a lack of early microbial exposure is associated with an imbalance in the neonatal development of T helper (Th)1, Th2 cells, and regulatory T cells (Treg), contributing to the increased … Continue reading →

The large heterogeneity in results might be explained by several factors. First, it is apparent that different probiotic strains or combinations of probiotics would be expected to elicit different effects. This explanation is insufficient, however, based on the observation that … Continue reading →

Eczema is the most common inflammatory skin condition in children and contributes significantly to childhood morbidity. The prevalence of allergic diseases among children, including eczema, has more than doubled during the past few decades and continues to rise.4 Furthermore, childhood … Continue reading →

Abstract The prevalence of eczema has increased during the past few decades and continues to rise. Furthermore, childhood eczema is associated with the development of allergy later in life. As a result, there is considerable interest in identifying effective treatments … Continue reading →